The mDOT Center

Transforming health and wellness via temporally-precise mHealth interventions
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21 Dec

SP 7: A Micro-Randomized Trial to Optimize Just-in-Time Adaptive Intervention for Binge Eating & Weight-related Behaviors

by mDOT Center
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/*! elementor - v3.18.0 - 08-12-2023 */.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=".svg"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block} Collaborating Investigator: Dr. Andrea K. Graham (PI), Northwestern Medicine Funding Status: R01DK133300 NIH/NIDDK Associated with: TR&D2 /*! elementor - v3.18.0 - 08-12-2023 */.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container{height:100%;width:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty,.e-con>.elementor-widget-spacer.elementor-widget-empty{position:relative;min-height:22px;min-width:22px}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon,.e-con>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon{position:absolute;top:0;bottom:0;left:0;right:0;margin:auto;padding:0;width:22px;height:22px} Summary TR&D Service Two in five U.S. adults have obesity, and up to 30% of treatment-seeking adults with obesity engage in binge eating, an eating disorder behavior characterized by eating a large amount of food and experiencing a...

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21 Dec

SP 8: Toward Optimizing Digital Mental Health Interventions: A Clinical Trial Aimed at Understanding What Drives Patient Engagement

by mDOT Center
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/*! elementor - v3.18.0 - 08-12-2023 */.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=".svg"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block} Collaborating Investigator: Jessica Lipschitz (PI), Brigham & Women's Hospital Funding Status: K23MH120324 NIH/NIMH 4/9/20-3/31/25 Associated with: TR&D2 /*! elementor - v3.18.0 - 08-12-2023 */.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container{height:100%;width:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty,.e-con>.elementor-widget-spacer.elementor-widget-empty{position:relative;min-height:22px;min-width:22px}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon,.e-con>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon{position:absolute;top:0;bottom:0;left:0;right:0;margin:auto;padding:0;width:22px;height:22px} Summary TR&D Service Depression and anxiety are highly comorbid and costly diseases. Evidence-based psychotherapy is the first-line treatment, but is underutilized and not scalable. Digital mental health interventions (DMHIs), delivered via the internet and/or mobile apps, have...

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05 Jun

SP 6: Computational Photo-Scatterography: Unraveling Scattered Photons for Bio-Imaging

by mDOT Center
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/*! elementor - v3.11.5 - 14-03-2023 */.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=".svg"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block} Collaborating Investigator: Dr. Ashutosh Sabharwal (PI), Rice University Funding Status: IIS-1730574 NSF/IIS 3/1/18 - 2/28/23 Associated with: TR&D3 /*! elementor - v3.11.5 - 14-03-2023 */.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))} Summary TR&D Service Imaging of human body at cellular-level at various depths below the skin can fundamentally impact healthcare by providing live views of cross sections of anatomy. However, current methods to achieve cellular resolution are invasive (e.g....

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05 Jun

SP 5: Engineering a Just-In-Time Adaptive Smoking Cessation Intervention using NCI’s QuitGuide Mobile Application

by mDOT Center
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/*! elementor - v3.11.5 - 14-03-2023 */ .elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=".svg"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block} Collaborating Investigator: Dr. Sherine El-Toukhy, NHLBI Funding Status: K99MD011755 NIH/NIMHD 8/1/17 -7/3 1/22 Associated with: TR&D2 /*! elementor - v3.11.5 - 14-03-2023 */ .elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))} Note: Dr. El-Toukhy recently became a Stadtman Investigator at the National Institute on Minority Health and Health Disparities. As this position provides the equivalent of an R01 funding from the intramural division of NIH annually, she gave up the above...

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05 Jun

SP 4: SMART Weight Loss Management

by mDOT Center
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/*! elementor - v3.11.5 - 14-03-2023 */.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=".svg"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block} Collaborating Investigators: Dr. Bonnie Spring (CO-PI), Northwestern University Dr. Inbal Nahum-Shani, University of Michigan Funding Status: R01 DK108678 NIH/NIDDK 2016 - 2021 Associated with: TR&D2 /*! elementor - v3.11.5 - 14-03-2023 */.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))} Summary TR&D Service Obesity’s high prevalence and costs make it a public health crisis, but standard of care treatment impedes uptake and depletes resources by taking a one-size-fits-all approach. Guidelines recommend...

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05 Jun

SP 3: Overeating in Obesity through the Lense of Passive Sensing

by mDOT Center
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/*! elementor - v3.11.5 - 14-03-2023 */ .elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=".svg"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block} Collaborating Investigator: Dr. Nabil Alshurafa, Northwestern University Funding Status: 1K25DK113242-01A1 NIH/NIDDK 1/1/18 - 11/30/22 Associated with: TR&D1 /*! elementor - v3.11.5 - 14-03-2023 */ .elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))} Summary TR&D Service Obesity, caused primarily by overeating relative to need, is a preventable chronic disease that exacts staggering healthcare costs. SP4 aims to identify eating patterns via wearable sensor data that characterize episodes of excess calorie intake. This...

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05 Jun

SP 1: Adaptive Platform for Personalized Engagement (All of Us Participant Technology Systems Center)

by mDOT Center
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/*! elementor - v3.11.5 - 14-03-2023 */ .elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=".svg"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block} Collaborating Investigator: Praduman Jain, Vibrent Health Funding Status: U24OD023163 NIH/OD 5/1/17 - 4/30/22 Associated with: TR&D1, TR&D3 /*! elementor - v3.11.5 - 14-03-2023 */ .elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))} Summary TR&D Service The All of Us Research Program is a key element of the Precision Medicine Initiative (PMI). Through advances in research, technology, and policies that empower patients, the PMI will enable a new era of medicine in which researchers, health...

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05 Jun

SP 2: Socioeconomic Status, Stress, and Smoking Cessation

by mDOT Center
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/*! elementor - v3.11.5 - 14-03-2023 */ .elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=".svg"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block} Collaborating Investigators: Dr. Cho Lam (PI), University of Utah Dr. David Wetter, University of Utah Funding Status: R01CA190329 NIH/NCI 7/1/15 – 6/30/21 Associated with: TR&D1 /*! elementor - v3.11.5 - 14-03-2023 */ .elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))} Summary TR&D Service SP2 is examining the influence of demographics and social history, biobehavioral and psychosocial predispositions, contextual and environmental factors, and acute individual and contextual precipitants on stress, smoking lapse, and...

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05 Jun

CP 8: Center for Methodologies for Adapting and Personalizing Prevention, Treatment and Recovery Services for SUD and HIV (MAPS Center)

by mDOT Center
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/*! elementor - v3.18.0 - 08-12-2023 */ .elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=".svg"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block} Collaborating Investigator:Dr. Inbal Nahum-Shani, University of Michigan Funding Status: P50DA054039-01NIH/NIDA9/1/21 - 6/30/26 Associated with:TR&D2 /*! elementor - v3.18.0 - 08-12-2023 */ .elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container{height:100%;width:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty,.e-con>.elementor-widget-spacer.elementor-widget-empty{position:relative;min-height:22px;min-width:22px}.e-con-inner>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon,.e-con>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon{position:absolute;top:0;bottom:0;left:0;right:0;margin:auto;padding:0;width:22px;height:22px} ...

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05 Jun

CP 7: mProv: Provenance-based Data Analytics Cyberinfrastructure for High-frequency Mobile Sensor Data

by mDOT Center
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/*! elementor - v3.11.5 - 14-03-2023 */.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=".svg"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block} Collaborating Investigator: Dr. Zach Ives, University of Pennsylvania (PI: Dr. Santosh Kumar, University of Memphis) Funding Status: ACI-1640183 NSF/ACI 9/01/16 - 8/31/21 Associated with: TR&D3 /*! elementor - v3.11.5 - 14-03-2023 */.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))} Significance Approach & Push Pull Relationship There are major hurdles to using mobile sensor data to advance research on computational modeling of human health and behavior, including lack of access to...

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The mHealth Center for Discovery, Optimization & Translation of Temporally-Precise Interventions is supported by the National Institutes

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